Chromosome Evil 2 similar games & best alternatives

Chromosome Evil 2 - chromosome-evil-2_1.avif
Chromosome Evil 2 - chromosome-evil-2_2.avif
Chromosome Evil 2 - chromosome-evil-2_3.avif
Chromosome Evil 2 - chromosome-evil-2_4.avif
Chromosome Evil 2 - chromosome-evil-2_5.avif
Chromosome Evil 2 - chromosome-evil-2_6.avif

Chromosome Evil 2

PC (Microsoft Windows) • 2024

Should you play it?

Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

What works

  • Deep tactical and strategic gameplay
  • Meaningful resource and squad management
  • Multiple endings and replayability
  • Active developer support and frequent updates
  • Accessible on low-end pcs

Things to keep in mind

  • Numerous bugs and crashes reported
  • Clunky ui and inventory management
  • Pathfinding and unit movement issues
  • Steep learning curve and grind
  • Some balance issues with ammo scarcity and enemy difficulty spikes

What to play next

Top picks

Games that feel the closest overall

  • Chromosome Evil

  • Space Hulk: Ascension (Classic)

  • Lords of Magic: Special Edition

  • Elemental: Reforged

  • Rencounter

  • Seer's Gambit

  • Twilight Wars

  • Warhammer 40,000: Chaos Gate - Daemonhunters

  • Langrisser I & II

Search more ->

Hidden Gems

Less popular games with surprisingly high similarity

  • Vestaria Saga II: The Sacred Sword of Silvanister

  • The Caligula Effect 2

  • Voidspire Tactics

If you liked…

Recommendations by what you enjoyed most

  • Strategy

    Deity Empires
  • Survival

    NEO Scavenger
  • Autonomy

    Phoenix Point

Similarity map

Explore nearby similar games and see why they’re close.

How to use the graph

Similarity map

Each dot is a game. They are arranged from the game’s motivation profile. Closer dots usually mean more similar reasons to play (exploration, competition, relaxation, etc.)—not that one game is “better” than another.

  • Purple star: this page’s game — everything on the map is relative to it.
  • Coloured chips: click to highlight games that mainly differ on that motivation; click again to reset.
  • Dotted line: link between this page’s game and the one selected for comparison.
  • Hover a dot to preview that game in the panel on the right; click to keep that comparison.
  • Scroll or double-click the chart to zoom out and see more games.

Why don’t the axes read like a score? This view uses t-SNE: it only keeps who is close to whom. The scales are not “good to bad” or hours played—they separate groups on the map. Read distance between dots, not the axis numbers (hidden on purpose).

Chromosome Evil 2: Broadly representative of its motivational profile, with a few distinct shifts. Motivations that often define this kind of title include Survival, Violence, Fellowship, Intimacy. Here, the score leans higher than usual among comparable games on Cooperation, Leadership. It leans lower than usual among comparable games on Relaxation.

Last update: 26/07/2026